Herb/Drug Interaction Table
click on a drug name to see description

5-hydroxytryptophan can potentiate the SSRIs and interact with MAOIs increasing the risk for SS	CITALOPRAM HYDROBROMIDE ESCITALOPRAM OXALATE FLUOXETINE HYDROCHLORIDE FLUVOXAMINE MALEATE PAROXETINE HYDROCHLORIDE PHENELZINE SERTRALINE HYDROCHLORIDE TRANYLCYPROMINE
acacia high fiber herb thus potential to decreases drug absorption if taken together	MOST DRUGS
aloe potential to prompt potassium loss when coupled with certain drugs, can enhance therapeutic effects of hypoglycemic agents	ACARBOSE ACETOHEXAMIDE ADENOSINE AMIODARONE HYDROCHLORIDE BRETYLIUM TOSYLATE CHLORPROPAMIDE CORTICOSTEROIDS DIGOXIN FLECAINIDE ACETATE GLIMEPIRIDE GLIPIZIDE GLYBURIDE INSULIN LIDOCAINE HYDROCHLORIDE METFORMIN HYDROCHLORIDE NATEGLINIDE PIOGLITAZONE HYDROCHLORIDE PROCAINAMIDE HYDROCHLORIDE QUINIDINE REPAGLINIDE ROSIGLITAZONE MALEATE TOLAZAMIDE TOLBUTAMIDE
angelica can increase the SE of photosensitivity drugs	HYDROCHLOROTHIAZIDE
artichoke increase effect of cholesterol lowering drugs	ATORVASTATIN CALCIUM FLUVASTATIN SODIUM LOVASTATIN PRAVASTATIN SODIUM ROSUVASTATIN SIMVASTATIN
astragalus can block the action of immune suppressant drugs	BECLOMETHASONE DIPROPIONATE BETAMETHASONE DIPROPIONATE BETAMETHASONE VALERATE CORTICOSTEROIDS CYCLOSPORINE DEXAMETHASONE HYDROCORTISONE METHYLPREDNISOLONE PREDNISOLONE PREDNISONE TRIAMCINOLONE TRIAMCINOLONE
belladonna can increase the anticholinergic effect	AMIODARONE HYDROCHLORIDE AMITRIPTYLINE HYDROCHLORIDE CLOMIPRAMINE DESIPRAMINE HYDROCHLORIDE DOXEPIN HYDROCHLORIDE FLECAINIDE ACETATE IMIPRAMINE HYDROCHLORIDE MAPROTILINE HYDROCHLORIDE NORTRIPTYLINE HYDROCHLORIDE PROTRIPTYLINE HYDROCHLORIDE QUINIDINE TRIMIPRAMINE MALEATE
bitter melon can increase the effects of insulin and oral diabetes drugs	ACARBOSE ACETOHEXAMIDE CHLORPROPAMIDE GLIMEPIRIDE GLIPIZIDE GLYBURIDE INSULIN METFORMIN HYDROCHLORIDE NATEGLINIDE PIOGLITAZONE HYDROCHLORIDE REPAGLINIDE ROSIGLITAZONE MALEATE TOLAZAMIDE TOLBUTAMIDE
borage can increase hepatotoxic effects, additive effect to seizure threshold lowering drugs	ACETAMINOPHEN ALCOHOL BARBITURATES BENZODIAZEPINES BUPROPION HYDROCHLORIDE CLARITHROMYCIN ERYTHROMYCIN HYDANTOINS ISONIAZID METHOTREXATE SODIUM METHYLDOPA MISCELLANEOUS ANTICONVULSANTS NIACIN OXAZOLIDINEDIONES PHENYTOIN SODIUM STATIN DRUGS SUCCINIMIDES
caffiene binds with iron, can decrease effects of alkaloids	ATROPINE SULFATE BELLADONNA COX 2 INHIBITOR DESERPIDINE DIHYDROERGOTAMINE MESYLATE ERGOLOID MESYLATES ERGOTAMINE TARTRATE I-131 IPECAC IRON METHYSERGIDE MALEATE NONSTEROIDAL ANTIINFLAMMATORY DRUGS OPIOIDS QUININE SULFATE RESERPINE RESERPINE SCOPOLAMINE
calcium can decrease absorption of antibiotics, calcium channel blockers, diuretics, and seizure meds	MOST DRUGS
casara can interact with antiarrhythmic drugs with loss of potassium	ADENOSINE AMIODARONE HYDROCHLORIDE BRETYLIUM TOSYLATE CORTICOSTEROIDS DIGOXIN FLECAINIDE ACETATE LIDOCAINE HYDROCHLORIDE PROCAINAMIDE HYDROCHLORIDE QUINIDINE
cat's claw binds with iron, can decrease the effect of alkaloids	ATROPINE SULFATE BELLADONNA DESERPIDINE ERGOLOID MESYLATES ERGOTAMINE TARTRATE IPECAC IRON METHYSERGIDE MALEATE OPIOIDS QUININE SULFATE RESERPINE RESERPINE SCOPOLAMINE
cedar can decrease effect of anticonvulsants	BARBITURATES BENZODIAZEPINES HYDANTOINS MISCELLANEOUS ANTICONVULSANTS OXAZOLIDINEDIONES SUCCINIMIDES
celery seed can increase the diuretic effect of antiarrhythmic drugs with potential for potassium depletion	AMIODARONE HYDROCHLORIDE CORTICOSTEROIDS DIGOXIN FLECAINIDE ACETATE LITHIUM CARBONATE QUINIDINE
cinchona bark (quinine) can increase plasma levels of cardiac glycosides	DIGOXIN
clover can potentiate anticoagulants and increase bleeding	WARFARIN SODIUM
cocoa can decrease effect of insulin and oral diabetic agents	ACARBOSE ACETOHEXAMIDE CHLORPROPAMIDE GLIPIZIDE GLYBURIDE INSULIN METFORMIN HYDROCHLORIDE NATEGLINIDE PIOGLITAZONE HYDROCHLORIDE REPAGLINIDE ROSIGLITAZONE MALEATE TOLAZAMIDE TOLBUTAMIDE
coenzyme statin cholesterol lowering drugs can deplete this enzyme in the body and decrease absorption	ATORVASTATIN CALCIUM FIBRIC DRUGS FLUVASTATIN SODIUM LOVASTATIN PRAVASTATIN SODIUM ROSUVASTATIN SIMVASTATIN WARFARIN SODIUM
cohosh, black has phytoestrogens	ESTROGENS
collard can decrease the effect of anticoagulant drugs and increase clotting	WARFARIN SODIUM
colt's foot can increase effect of hepatotoxic drugs	ACETAMINOPHEN ALCOHOL CLARITHROMYCIN ERYTHROMYCIN ISONIAZID METHOTREXATE SODIUM METHYLDOPA NIACIN PHENYTOIN STATIN DRUGS
comfrey can increase the side effect of hepatotoxic drugs	ACETAMINOPHEN ALCOHOL CLARITHROMYCIN ERYTHROMYCIN ISONIAZID METHOTREXATE SODIUM METHYLDOPA NIACIN PHENYTOIN STATIN DRUGS
corn silk can increase diuretic effect of antiarrhythmic and corticosteriod drugs and deplete potassium	AMIODARONE HYDROCHLORIDE CORTICOSTEROIDS DIGOXIN FLECAINIDE ACETATE LITHIUM CARBONATE QUINIDINE
cramp bark can increase the effect of anticonvulsants	BARBITURATES BENZODIAZEPINES HYDANTOINS METHOTREXATE SODIUM MISCELLANEOUS ANTICONVULSANTS OXAZOLIDINEDIONES SUCCINIMIDES
current, black additive effect to seizure threshold lowering drugs	BARBITURATES BENZODIAZEPINES BUPROPION HYDROCHLORIDE HYDANTOINS MISCELLANEOUS ANTICONVULSANTS OXAZOLIDINEDIONES SUCCINIMIDES
danshen can potentiate coumarin anticoagulants and increase bleeding	WARFARIN SODIUM
echinacea can block action of immune suppressants	BECLOMETHASONE DIPROPIONATE BETAMETHASONE DIPROPIONATE BETAMETHASONE VALERATE CORTICOSTEROIDS CYCLOSPORINE DEXAMETHASONE HYDROCORTISONE METHYLPREDNISOLONE PREDNISOLONE PREDNISONE TRIAMCINOLONE TRIAMCINOLONE
ephedra BANNED, but still available via internet, decrease antihypertensive drug action and markedly increase BP	ALPRAZOLAM BETA ADRENERGIC BLOCKING AGENTS CALCIUM-CHANNEL BLOCKING AGENTS RENIN-ANGIOTENSIN SYSTEM INHIBITORS
evening primrose additive effect to seizure threshold lowering drugs	BARBITURATES BENZODIAZEPINES BUPROPION HYDROCHLORIDE HYDANTOINS MISCELLANEOUS ANTICONVULSANTS OXAZOLIDINEDIONES SUCCINIMIDES
fennel can increase effect of insulin and oral diabetic drugs and photosensitizing drugs	HYDROCHLOROTHIAZIDE
fenugreek can increase effect of cholesterol lowering drugs, has phytoestrogens	ACARBOSE ACETOHEXAMIDE ATORVASTATIN CALCIUM CHLORPROPAMIDE ESTROGENS FLUVASTATIN SODIUM GLIMEPIRIDE GLIPIZIDE GLYBURIDE INSULIN LOVASTATIN METFORMIN HYDROCHLORIDE NATEGLINIDE PIOGLITAZONE HYDROCHLORIDE PRAVASTATIN SODIUM REPAGLINIDE ROSIGLITAZONE MALEATE ROSUVASTATIN SIMVASTATIN TOLAZAMIDE TOLBUTAMIDE
feverfew can potentiate antiplatlet and anticoagulant drugs and increase bleeding	HEPARIN SODIUM WARFARIN SODIUM
flax in seed form the fiber can interfere with absorption of most drugs, take separately	MOST DRUGS
fox glove herb is a cardiac glycoside, will increase effect of drug cardiac glycosides	DIGOXIN
garlic can increase absorption of statins and effect of antiplatlet, anticoagulant, and vasodialator drugs, enhance hypoglycemics	ACARBOSE ACETOHEXAMIDE ASPIRIN CHLORPROPAMIDE GLIMEPIRIDE GLIPIZIDE GLYBURIDE HEPARIN SODIUM INSULIN METFORMIN HYDROCHLORIDE MOST DRUGS NATEGLINIDE PIOGLITAZONE HYDROCHLORIDE REPAGLINIDE ROSIGLITAZONE MALEATE TOLAZAMIDE TOLBUTAMIDE WARFARIN SODIUM
ginger can increase effect of antiplatlet, anticoagulant, cholesterol lowering, and vasodialators drugs	ASPIRIN ATORVASTATIN CALCIUM FLUVASTATIN SODIUM HEPARIN SODIUM LOVASTATIN MOST DRUGS PRAVASTATIN SODIUM ROSUVASTATIN SIMVASTATIN WARFARIN SODIUM
gingko can potentiate antiplatlet and anticoagulant drugs and increase bleeding, also increase MAOI	ASPIRIN HEPARIN SODIUM PHENELZINE TRANYLCYPROMINE WARFARIN SODIUM
ginseng (panax) can decrease effect of diuretics and opioids, increase effect of cardiac glycosides and MAOIs	ACARBOSE ACETOHEXAMIDE ASPIRIN CHLORPROPAMIDE CORTICOSTEROIDS DIGOXIN ESTROGENS FUROSEMIDE GLIMEPIRIDE GLIPIZIDE GLYBURIDE HEPARIN SODIUM INSULIN METFORMIN HYDROCHLORIDE NATEGLINIDE OPIOIDS PIOGLITAZONE HYDROCHLORIDE REPAGLINIDE ROSIGLITAZONE MALEATE TOLAZAMIDE TOLBUTAMIDE WARFARIN SODIUM
ginseng (siberian) can increase blood levels of digoxin	DIGOXIN
gymnema can interfere with diabetic agents	ACARBOSE ACETOHEXAMIDE CHLORPROPAMIDE GLIMEPIRIDE GLIPIZIDE GLYBURIDE INSULIN METFORMIN HYDROCHLORIDE NATEGLINIDE PIOGLITAZONE HYDROCHLORIDE REPAGLINIDE ROSIGLITAZONE MALEATE TOLAZAMIDE TOLBUTAMIDE
hops additive effect to sedatives and hypnotics	OPIOIDS
horseradish can decrease effect of thyroid hormone replacement therapy	LEVOTHYROXINE SODIUM LIOTHYRONINE SODIUM THYROID
horsetail can increase sodium loss with lithium, can increase diuretic effect of cardiac drugs and corticosteroids	AMIODARONE HYDROCHLORIDE CORTICOSTEROIDS DIGOXIN FLECAINIDE ACETATE LITHIUM CARBONATE QUINIDINE
juniper can increase sodium loss with lithium, can increase diuretic effect of cardiac drugs and corticosteroids	AMIODARONE HYDROCHLORIDE CORTICOSTEROIDS DIGOXIN FLECAINIDE ACETATE LITHIUM CARBONATE QUINIDINE
kale can decrease effect of anticoagulant drugs and increase clotting	WARFARIN SODIUM
kava can have an additive effect on anesthetics, benzodiazepines, hypnotics, sedatives	ACETAMINOPHEN ALCOHOL ALPRAZOLAM BUSPIRONE HYDROCHLORIDE BUTABARBITAL SODIUM CHLORAL HYDRATE CITALOPRAM HYDROBROMIDE CLARITHROMYCIN CLORAZEPATE DIPOTASSIUM CLORAZEPATE DIPOTASSIUM DIAZEPAM ERYTHROMYCIN ESTAZOLAM FLURAZEPAM HYDROCHLORIDE HYDROXYZINE HYDROCHLORIDE ISONIAZID LORAZEPAM MEPHOBARBITAL MEPROBAMATE METHOTREXATE SODIUM METHYLDOPA MIDAZOLAM HYDROCHLORIDE NIACIN OPIOIDS OXAZEPAM PENTOBARBITAL PHENOBARBITAL PHENYTOIN QUAZEPAM SECOBARBITAL SODIUM STATIN DRUGS TEMAZEPAM TRIAZOLAM
kelp can increase the effect of thyroid replacement therapy	LEVOTHYROXINE SODIUM LIOTHYRONINE SODIUM THYROID
kyushin increases serum levels of digoxin	DIGOXIN
L-arginine Argatroban is a derivative of L-arginine and is used as an anticoagulant, simultaneous use may increase bleeding time.	ARGATROBAN
licorice can decrease BP med effect and raise BP, increase effect of antiarrhythmics, diuretics, & MAOI, increase insomnia with corticosteroids	ALPHA ADRENERGIC BLOCKING AGENTS AMIODARONE HYDROCHLORIDE BETA ADRENERGIC BLOCKING AGENTS CALCIUM-CHANNEL BLOCKING AGENTS CORTICOSTEROIDS DIGOXIN DIURETICS ESTROGENS FLECAINIDE ACETATE PHENELZINE QUINIDINE RENIN-ANGIOTENSIN SYSTEM INHIBITORS TRANYLCYPROMINE
lily of the valley can increase the effect of the cardiac glycosides	DIGOXIN
marshmallow a high fiber herb that can interfere with the absorption of most drugs if taken together	MOST DRUGS
milk thistle can interact with the antiretroviral medications used to suppress HIV	ABACAVIR AMPRENAVIR DELAVIRDINE MESYLATE DIDANOSINE DIDANOSINE EFAVIRENZ INDINAVIR SULFATE LAMIVUDINE LAMIVUDINE LOPINAVIR NELFINAVIR MESYLATE NEVIRAPINE RITONAVIR SAQUINAVIR STAVUDINE TENOFOVIR ZIDOVUDINE
nettles (stinging) can decrease effect of insulin and oral diabetic agents, can increase action of NSAIDs	ACARBOSE ACETOHEXAMIDE CHLORPROPAMIDE COX 2 INHIBITOR GLIPIZIDE GLYBURIDE INSULIN METFORMIN HYDROCHLORIDE NATEGLINIDE NONSTEROIDAL ANTIINFLAMMATORY DRUGS PIOGLITAZONE HYDROCHLORIDE REPAGLINIDE ROSIGLITAZONE MALEATE TOLAZAMIDE TOLBUTAMIDE
pepper (black,red) increae the absorption of vasodialators	MOST DRUGS
poppy (California, opium) can increase the effect of sedatives and hypnotics	OPIOIDS
psyllium high fiber substance that can markedly decrease absorption of most drugs taken with it , especially minerals	MOST DRUGS
rosemary can decrease effect of insulin and oral diabetic agents	ACARBOSE ACETOHEXAMIDE CHLORPROPAMIDE GLIPIZIDE GLYBURIDE INSULIN METFORMIN HYDROCHLORIDE NATEGLINIDE PIOGLITAZONE HYDROCHLORIDE REPAGLINIDE ROSIGLITAZONE MALEATE TOLAZAMIDE TOLBUTAMIDE
rue can increase the gastrointestinal side effects of NSAIDs, also increase side effect of photosensitivity drug effect	ACETAMINOPHEN ALCOHOL CLARITHROMYCIN COX 2 INHIBITOR ERYTHROMYCIN HYDROCHLOROTHIAZIDE ISONIAZID METHOTREXATE SODIUM METHYLDOPA NIACIN NONSTEROIDAL ANTIINFLAMMATORY DRUGS PHENYTOIN STATIN DRUGS
sage can decrease the effect of anticonvulsant drugs	BARBITURATES BENZODIAZEPINES HYDANTOINS MISCELLANEOUS ANTICONVULSANTS OXAZOLIDINEDIONES SUCCINIMIDES
saint johns wort (hypericum) can decrease effect of anticoagulants, antiretrovirals, benzodiazepines, cardiac glycosides; can increase effects of photosensitizing drugs and the MAO & serotonin-reuptake inhibitor antidepressants	ABACAVIR ALPRAZOLAM AMPRENAVIR CITALOPRAM HYDROBROMIDE CITALOPRAM HYDROBROMIDE CLORAZEPATE DIPOTASSIUM CLORAZEPATE DIPOTASSIUM DELAVIRDINE MESYLATE DIAZEPAM DICUMAROL DIDANOSINE DIDANOSINE DIGOXIN EFAVIRENZ ESCITALOPRAM OXALATE ESTAZOLAM FLUOXETINE HYDROCHLORIDE FLURAZEPAM HYDROCHLORIDE FLUVOXAMINE MALEATE HYDROCHLOROTHIAZIDE INDINAVIR SULFATE LAMIVUDINE LAMIVUDINE LOPINAVIR LORAZEPAM MIDAZOLAM HYDROCHLORIDE NEFAZODONE HYDROCHLORIDE NELFINAVIR MESYLATE NEVIRAPINE OXAZEPAM PAROXETINE HYDROCHLORIDE PHENELZINE QUAZEPAM RITONAVIR SAQUINAVIR SERTRALINE HYDROCHLORIDE STAVUDINE TEMAZEPAM TENOFOVIR THYAZIDE DIURETICS TRANYLCYPROMINE TRAZODONE HYDROCHLORIDE TRIAZOLAM WARFARIN SODIUM ZALCITABINE ZIDOVUDINE
senna can increase the effect of antiarrhythmic and cathartic laxatives with resultant potassium loss	ADENOSINE AMIODARONE HYDROCHLORIDE BRETYLIUM TOSYLATE CORTICOSTEROIDS DIGOXIN FLECAINIDE ACETATE LIDOCAINE HYDROCHLORIDE PROCAINAMIDE HYDROCHLORIDE QUINIDINE
slippery elm fiber content can decrease absorption of many drugs if taken together	MOST DRUGS
soy can decrease absorption of calcium and interfere with action of hormone replacement	ESTROGENS
spinach can decrease effect of anticoagulants and increase clotting	WARFARIN SODIUM
tansy can decrease effect of anticonvulsants and increase chance of seizure	ACETAMINOPHEN ALCOHOL BARBITURATES BENZODIAZEPINES CLARITHROMYCIN ERYTHROMYCIN HYDANTOINS ISONIAZID METHOTREXATE SODIUM METHYLDOPA MISCELLANEOUS ANTICONVULSANTS NIACIN OXAZOLIDINEDIONES PHENYTOIN STATIN DRUGS SUCCINIMIDES
tea (black, green) can bind with iron, decrease alkaloid effect	ATROPINE SULFATE BELLADONNA DESERPIDINE ERGOLOID MESYLATES ERGOTAMINE TARTRATE ERGOTAMINE TARTRATE IPECAC IRON METHYSERGIDE MALEATE OPIOIDS QUININE SULFATE RESERPINE RESERPINE SCOPOLAMINE
uva ursi can bind with iron, decrease effect of alkaloids and salicylate plasma levels, and increase GI side effects of NSAIDs	ASPIRIN ATROPINE SULFATE BELLADONNA COX 2 INHIBITOR DESERPIDINE ERGOLOID MESYLATES IPECAC IRON METHYSERGIDE MALEATE NONSTEROIDAL ANTIINFLAMMATORY DRUGS OPIOIDS QUININE SULFATE RESERPINE RESERPINE SCOPOLAMINE
valerian can have an additive effect to anesthetics, barbiturates, ethyl alcohol, sedative hypnotics	BUPROPION HYDROCHLORIDE BUTABARBITAL SODIUM CHLORAL HYDRATE HYDROXYZINE HYDROCHLORIDE MEPHOBARBITAL MEPROBAMATE OPIOIDS PENTOBARBITAL PHENOBARBITAL SECOBARBITAL SODIUM
willow can increase the effect of anticonvulsant drugs	BARBITURATES BENZODIAZEPINES HYDANTOINS METHOTREXATE SODIUM MISCELLANEOUS ANTICONVULSANTS OXAZOLIDINEDIONES SUCCINIMIDES
wintergreen can increase the plasma levels of anticonvulsant drugs & cytotoxic drugs like methotrexate risking toxicity	BARBITURATES BENZODIAZEPINES HYDANTOINS METHOTREXATE SODIUM MISCELLANEOUS ANTICONVULSANTS OXAZOLIDINEDIONES SUCCINIMIDES
yeast (red) can increase the effects of statin cholesterol lowering drugs and potentially increase adverse side effects	ATORVASTATIN CALCIUM FLUVASTATIN SODIUM LOVASTATIN PRAVASTATIN SODIUM ROSUVASTATIN SIMVASTATIN
yellow dock can increase the diuretic effect of antiarrhythmic drugs, cardiac glycosides, cathartic laxatives, and corticosteroids	ADENOSINE AMIODARONE HYDROCHLORIDE BRETYLIUM TOSYLATE CORTICOSTEROIDS DIGOXIN FLECAINIDE ACETATE LIDOCAINE HYDROCHLORIDE PROCAINAMIDE HYDROCHLORIDE QUINIDINE
yohimbe can inhibit monoamine oxidase (MAO) and have an additive effect to drugs with this action (MAOI drugs) and over the counter cold meds containing phenylpropanolamine	CITALOPRAM HYDROBROMIDE ESCITALOPRAM OXALATE FLUOXETINE HYDROCHLORIDE NEFAZODONE HYDROCHLORIDE PAROXETINE HYDROCHLORIDE PHENELZINE SERTRALINE HYDROCHLORIDE TRANYLCYPROMINE TRAZODONE HYDROCHLORIDE

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